Coming off a GLP-1

For a lot of people, stopping is part of the arc — planned, or forced by cost, supply or side effects. This page is about what changes and what is worth having written down. Whether and when to stop is a decision for you and your prescriber, and nothing here weighs in on it.

This page does not have an opinion on stopping

That has to be said plainly, because most of what you will find on this subject is trying to talk you into or out of something. Whether to taper, how fast, and what to do afterwards are medical decisions that depend on why you started, what else you take and what your clinician sees. We track; we do not advise.

The medicine leaves over weeks, not days

These are long-acting drugs. After a last dose, levels fall gradually rather than switching off — which is why the days right after a missed or final injection often feel like nothing has changed, and why what people notice tends to arrive later than they expect. If you want the actual numbers, our calculator site has a plain-language half-life page with cited figures.

Appetite usually speaks before the scale does

The thing people most often report noticing first is not weight — it is food noise coming back: the mental chatter about food that had gone quiet. It tends to return before the trend line does anything at all. That gap is exactly why a written record beats memory here; by the time the scale moves, the earlier change is weeks old and easy to misremember.

What's worth having a record of

Your dose history and the date of the last one. The weight trend, not single readings. Food noise, week by week. Side effects — some fade, and knowing which and when is useful. What you were actually eating, especially protein. None of this is a plan; it is the raw material for the conversation you will have with whoever prescribes for you.

Then there's the next time

People restart. Cost changes, supply returns, circumstances change. The single most useful thing you can bring to that decision is what happened for you last time — which dose you were on when things settled, how quickly appetite came back, which side effects showed up and when. That is personal data no study can give you, and it only exists if somebody wrote it down. Glipath's off-ramp tracking is built for exactly this stretch, and it stays on your phone.

Educational content only — not medical advice, and never a recommendation about starting, changing or stopping a medication. Talk to your provider or pharmacist about anything that applies to you.

Track the whole arc, including the way down